Neuropeptides: keeping the balance between pathogen immunity and immune tolerance
نویسندگان
چکیده
منابع مشابه
Dendritic cells and the balance between transplant tolerance and immunity _
Dendritic cells (DC) are a distinct lineage of unusually potent accessory cells for immune responses (reviewed in [1-4]) that are derived from CD34+ bone marrow precursors. They possess, or can acquire, the capacity to initiate primary adaptive immune responses in vitro and in vivo. This property is ascribed to expression of high cell surface levels of major histocompatibility complex (MHC) cla...
متن کاملQuantitative PPARγ expression affects the balance between tolerance and immunity
PPARγ modulates energy metabolism and inflammation. However, its specific functions in the balance of immunity in vivo have been explored incompletely. In this study, by the age of 14 mo, Pparg(C/-) mice with PPARγ expression at 25% of the normal level exhibited high autoantibody levels and developed mesangial proliferative glomerulonephritis, which resembled systemic lupus erythematosus (SLE)-...
متن کاملImmune system: part III. The delicate balance of the immune system between tolerance and autoimmunity.
The immune system consists of an intricate network of organs, cells, and molecules responsible for maintaining the body's homeostasis and responding to aggression in general. Innate immunity operates in conjunction with adaptive immunity and is characterized by rapid response to aggression, regardless of previous stimulus, being the organism first line of defense. Its mechanisms include physica...
متن کاملKeeping the Balance Between Proliferation and Differentiation: The Primary Cilium
Primary cilia are post-mitotic cellular organelles that are present in the vast majority of cell types in the human body. An extensive body of data gathered in recent years is demonstrating a crucial role for this organelle in a number of cellular processes that include mechano and chemo-sensation as well as the transduction of signaling cascades critical for the development and maintenance of ...
متن کاملThe balance between immunity and inflammation.
G R A P H IC : V . A L T O U N IA N / S C IE N C E straints on the primordial size distribution of the asteroids. The newest models that started the whole debate suggest that planetesimals form through the clumping of small particles (1, 2), predicting that asteroids that form should initially be of large size. Morbidelli et al. (6) modeled asteroid formation and found that to reproduce the exi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Opinion in Pharmacology
سال: 2010
ISSN: 1471-4892
DOI: 10.1016/j.coph.2010.03.003